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Glycyrrhiza glabra
go.drugbank.com/drugs/DB14312ApprovedInvestigationalWithdrawnIt is not an approved drug.
Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic ExtractButoconazole
go.drugbank.com/drugs/DB00639ApprovedButoconazole is an imidazole antifungal used in gynecology.
Denileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigational[A264349, L51254] Denileukin diftitox was originally approved by the FDA in 1999 for the treatment of cutaneous T-cell lymphoma (CTCL),[A264339, L51264] making it the first fusion protein cytotoxin … on August 8, 2024.
Synonyms: N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2, N-L-METHIONYL-387-L-HISTIDINE-388-L-ALANINE-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE STRAIN C7) (388->2') PROTEIN WITH 2-133-INTERLEUKIN 2 (HUMAN CLONE PTIL2-21A)Imlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigational[L54046] Imlunestrant works by antagonizing ER transcriptional activity and, by forming an unstable drug-receptor complex, promotes ER degradation via the ubiquitin-proteasome pathway. … progression on at least one line of endocrine therapy.
Indium In-111 satumomab pendetide
go.drugbank.com/drugs/DB00057ApprovedWithdrawnSatumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Copper oxodotreotide Cu-64
go.drugbank.com/drugs/DB15873Approved[A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution. … [A220348] Further studies should be performed to compare the two tracers.
Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: N-phenethyl-4-(N-propionylanilino)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamideDiclofenamide
go.drugbank.com/drugs/DB01144ApprovedA carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Garadacimab
go.drugbank.com/drugs/DB15629Approved[A273993] In June 2025, garadacimab was approved by the US FDA for the prophylaxis of HAE episodes in patients ≥12 years of age. … [L53303,L53283] It is the first inhibitor of factor XIIa to receive market approval.[L53303]
Xanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigational[A264514] Xanomeline is a muscarinic agonist that was approved for the treatment of schizophrenia by the FDA in September 2024, becoming the first approved treatment for schizophrenia to target muscarinic … receptors as opposed to dopamine receptors.