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Coenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Categories: Compounds used in a research, industrial, or household settingSynonyms: Coenzym M, Coenzima MCarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalCarbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, deamino-2-O-methyltyrosine-1-carbaoxytocinProducts: KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, PABAL 100 MCG/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 ADETAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalEndogenous Factor VIII is essential to the clotting process in the body due to its involvement in the clotting cascade where it is responsible for acting as a co-factor to Factor IX. … Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of
Mixtures: BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI, BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICICategories: Hemophilia ADeoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Mixtures: Duchol Ect, Debiline HSynonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acidEmpagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigational[A203501] Attempts at overcoming these limitations first saw the development of O-glucoside analogs of phlorizin (e.g. … [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus.
Mixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MGCategories: P-glycoprotein substrates, Sodium-Glucose Transporter 2 InhibitorsPolidocanol
go.drugbank.com/drugs/DB06811ApprovedInvestigationalPolidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower … It is marketed under the brand names Asclera and Varithena.
Mixtures: KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADET, DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 10 GCategories: Compounds used in a research, industrial, or household settingAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … [A234044] It plays an essential function in calcium homeostasis and bone metabolism.
Categories: Vitamin D and AnaloguesSynonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diol, 1-hydroxycholecalciferolPermethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate, 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl esterTerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigationalTerlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding.[A252672] The drug was first approved by the FDA in September 2022.[L43217]
Products: GLYPRESSIN 1 MG/8,5 ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 5 ADET, HAEMOPRESSIN® 1 MGAphidicolin
go.drugbank.com/drugs/DB17742ExperimentalIt inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Synonyms: 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3.alpha.,4.alpha.,5.alpha.,17.alpha.)-, 8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3r,4r,4ar,6as,8r,9r,11as,11bs)-