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Omiganan
go.drugbank.com/drugs/DB06610InvestigationalOmiganan has been investigated for the treatment of Mupirocin-resistant MRSA skin infections.
Categories: Pore Forming Cytotoxic ProteinsFaricimab
go.drugbank.com/drugs/DB15303ApprovedInvestigationaltarget VEGF-A. … [L42305] In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended faricimab be granted marketing authorization for the treatment of neovascular age-related macular degeneration
Products: VABYSMO 6mg/0.05mL Solution for Intravitreal InjectionTaliglucerase alfa
go.drugbank.com/drugs/DB08876ApprovedIt was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Burosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalMost children with XLH suffer from bowed or bent legs, short stature, bone pain and severe dental pain. … XLH is a serious disease which affects about 3,000 children and 12,000 adults in the United States.
Categories: Drugs for Treatment of Bone DiseasesProducts: CRYSVITA 10 MG SOLUTION FOR INJECTION, CRYSVITA 20 MG SOLUTION FOR INJECTIONFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIt is used as an appetite suppressant and a treatment for obesity. … effects are less notorious than with some other agents such as diethylpropion and mazindol. [7] In the United States fenproporex was never approved by the FDA for clinical use due to a lack of efficacy
Products: IFA-DIETY A. P.Allogeneic Cardiosphere-Derived Cells
go.drugbank.com/drugs/DB15744InvestigationalCDCs target multiple cytokine pathways associated with poor outcomes (e.g. TNFa, IFN-y, IL-1B, and IL-15). … Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic profile (CD105+, CD45-, and CD90low).
MAS825
go.drugbank.com/drugs/DB16452InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Taurolidine
go.drugbank.com/drugs/DB12473ApprovedInvestigationalTaurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. … and Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a limited and specific patient population.
Norflurane
go.drugbank.com/drugs/DB13116ApprovedInvestigationalWithdrawnNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Ipilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigationalIpilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).
Products: YERVOY 5 mg/ml concentrate for solution for infusion