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Icotrokinra
go.drugbank.com/drugs/DB21724ApprovedInvestigationalIcotrokinra is a first-in-class, targeted oral peptide and interleukin-23 (IL-23) receptor antagonist. … It was jointly discovered and developed by Protagonist and Johnson & Johnson[L56118] and provides a novel, oral treatment option for patients requiring systemic therapy for plaque psoriasis.
MC-1
go.drugbank.com/drugs/DB05315ExperimentalMedicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.
Synonyms: MC-1Umbralisib
go.drugbank.com/drugs/DB14989ApprovedInvestigationalWithdrawnWhile it initially offered a promising therapy for patients experiencing relapsing or refractory disease,[A229363] umbralisib was withdrawn from the market due to safety concerns as the drug was associated … It was marketed as Ukoniq by TG Therapeutics and has been approved for the treatment of relapsing and refractory marginal cell lymphoma and follicular lymphoma in adults.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMF-300
go.drugbank.com/drugs/DB32060InvestigationalMF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase. … As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]
Talc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalTalc is a mineral composed primarily of magnesium, silicon and oxygen. … It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders.
Mixtures: Spai-sons Fine TalcumCategories: Compounds used in a research, industrial, or household settingSparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigational>A</sub>R and 0.8 nM for AT<sub>1</sub>R). … Sparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub
Categories: Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA), Cytochrome P-450 SubstratesNomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Mixtures: ZOELY (2.5 MG/1.5 MG FILM-COATED TABLETS), FEMIDEN® 1.5 MG/2.5MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds. … Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis.
Mixtures: Isa Knox Ageless Serum Makeup Base 10, Gongjinhyang Mi Luxury BaseIsometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Mixtures: DIPIRONA 300 MG + ISOMETEPTENO 50 MG + CAFEINA 30 MG GOTAS, DIPIRONA SODICA 300 MG/ ISOMETEPTENO CLORHIDRATO 50 MG / CAFEINA 30 MG GOTASHexylresorcinol
go.drugbank.com/drugs/DB11254Approvedof which require further study and testing at the current moment. … The compound may also be used commonly in various commercial cosmetic anti-aging creams while ongoing studies research the possibility of using hexylresorcinol as an anti-cancer therapy - indications all