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Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalAn analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography. … Because of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.
Pyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalThis is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
Synonyms: Pyridoxal P, Pyridoxal-PMixtures: EnBrace HRSulfanilamide
go.drugbank.com/drugs/DB00259ApprovedWithdrawnSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: p-aminobenzenesulfamide, p-aminobenzenesulfonamideGanaxolone
go.drugbank.com/drugs/DB05087ApprovedInvestigationalindicated specifically for CDD. … [L41135] In July 2023, ganaxolone was also approved under the same brand name and for the same indication by the EMA.[L47636]
Categories: Cytochrome P-450 Substrates, Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive ModulatorN-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine
go.drugbank.com/drugs/DB13948ExperimentalIt has been tested with regard to the head-twitch-response (HTR) model of 5-HT2A activity and effects on locomotion [L1148]. It was discovered in 2014 at the University of Copenhagen.
Categories: Serotonin Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsNirsevimab
go.drugbank.com/drugs/DB16258ApprovedInvestigationalIn addition, nirsevimab was developed as a single-dose treatment for all infants experiencing their first RSV season, whereas palivizumab requires five monthly doses to cover an RSV season. … [L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 for the same indication.[L46392,L47461]
Categories: Antiinfectives for Systemic UseCopper histidinate
go.drugbank.com/drugs/DB32041ApprovedIt was approved by the US FDA in January 2026 for the treatment of pediatric patients with Menkes disease.[L54993,L54998] … [A275383] Copper histidinate is a subcutaneously-administered copper-histidine complex that allows for copper supplementation in patients with defective ATP7A transporters.
Copanlisib
go.drugbank.com/drugs/DB12483ApprovedInvestigational[A261730] Copanlisib was granted accelerated approval by the FDA in September 2017 for the treatment of follicular lymphoma.[A261725] … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesEdotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494Approved[L8603] Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).
Flunitrazepam
go.drugbank.com/drugs/DB01544ApprovedIllicitSome reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. … Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates