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Valethamate
go.drugbank.com/drugs/DB13497InvestigationalMixtures: EPIDOSIN COMPOSITUM 10 MG AMPUL, 3 ADET, EPIDOSIN COMPOSITUM ÇOCUKLARA, 5 ADETProducts: EPIMOL 8 MG/ML IM/IV ENJEKSIYONLUK COZELTI, 5 AMPUL, EPIDOSIN 8 MG/8 ML AMPUL, 5 ADETPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalIn the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat dandruff and seborrheic dermatitis. … While its use has been approved in the early 1960's by the FDA [A32163], safety and effectiveness of pyrithione zinc has been reported for decades.
Synonyms: Pyridinethiol N-oxide, 2-pyridinethiol 1-oxideMixtures: MD CELL Scalp, Carione RgOlopatadine
go.drugbank.com/drugs/DB00768ApprovedIt is a structural analog of [doxepin], which has a minimal anti-allergic activity. … An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively.
Mixtures: OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADETCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalIt also has a number of unique characteristics that have led to its increased use in the last two decades; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids … (due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanoneGadobutrol
go.drugbank.com/drugs/DB06703ApprovedInvestigationalGadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. … Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser injection volume.
Synonyms: gadolinium(III) 2,2',2''-(10-((2R,3S )-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetateCategories: Compounds used in a research, industrial, or household settingImiquimod
go.drugbank.com/drugs/DB00724ApprovedInvestigationalImiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain types of skin cancer called superficial basal cell carcinoma.
Synonyms: 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine, 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinolineMixtures: Imiquimod 5% / Niacinamide 4%, Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2%Fenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigationalFenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. … [L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Mixtures: SIMITRI® 145/40 MG, ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MGCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is also important medically because of its presence in tobacco smoke. … Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: (S)-3-(N-methylpyrrolidin-2-yl)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridineInosine pranobex
go.drugbank.com/drugs/DB13156ApprovedInosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3)Pindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigationalPindolol is a first generation non-selective beta blocker used in the treatment of hypertension. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Synonyms: 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-olInternational brands: Blockin L, Blocklin L