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Difelikefalin
go.drugbank.com/drugs/DB11938ApprovedInvestigationalPruritus associated with chronic kidney disease (also called uremic pruritus) affects 50-60% of all patients on dialysis and 25% of non-dialysis patients with chronic kidney disease. … with the administration of KOR antagonists.
Benznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Products: ABALEA ®100 MGTamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] … [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.
Products: NOVOFEN (10 MG), TAMOXIFENE EGCevimeline
go.drugbank.com/drugs/DB00185ApprovedIt is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Ecabet
go.drugbank.com/drugs/DB05265InvestigationalEcabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. … Ecabet is a prescription eye drop for the treatment of dry eye syndrome.
Categories: Compounds used in a research, industrial, or household settingTropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnAs a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting
Products: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - KapselnCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with congenital factor IX deficiency (Hemophilia B).
Mitoxantrone
go.drugbank.com/drugs/DB01204ApprovedInvestigationalAn anthracenedione-derived antineoplastic agent.
Products: MITOXANTRONE BAXTER INJECTION 2 mg/ml, MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETPerhexiline
go.drugbank.com/drugs/DB01074ApprovedPerhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Forasartan
go.drugbank.com/drugs/DB01342ExperimentalAs angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Agents Acting on the Renin-Angiotensin System