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Hydrocortisone probutate
go.drugbank.com/drugs/DB14543ApprovedVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersEteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigational[L40015] Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory or cardiac complications. … Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer.
Categories: Compounds used in a research, industrial, or household settingSynonyms: (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonylCannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalIt is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana [A32584]. … CBDV has also been shown to inhibit the activity of diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2-arachidonoylglycerol (2-AG) [A33296, A33347
Tradipitant
go.drugbank.com/drugs/DB12580ApprovedInvestigationalTradipitant is a selective, high-affinity antagonist at human substance P/neurokinin-1 (NK-1) receptors.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2C19 SubstratesHydrocortisone valerate
go.drugbank.com/drugs/DB14544ApprovedVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersBGB-DXP593
go.drugbank.com/drugs/DB16357InvestigationalBGB-DXP593 is a SARS-CoV-2 neutralizing antibody. … [L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants
Streptomycin
go.drugbank.com/drugs/DB01082ApprovedInvestigationalVet approved[A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as … Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: KRİSTALİZE STREPTOMİSİN SÜLFAT 1 G ENJEKSİYONLUK ÇÖZELTİ TOZU, 50 ADET, STREPTOMYCIN SULFATE FOR INJECTION 1 g/vialTrilaciclib
go.drugbank.com/drugs/DB15442ApprovedInvestigationalTrilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSplicing factor 3B subunit 1
go.drugbank.com/bio_entities/BE0009359TargetHumansComponent of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:32494006, PubMed:34822310, PubMed:36104565). The 17S U2...
Synonyms: SAP 155, Spliceosome-associated protein 155Daridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigational[A244225] It was approved by the FDA on January 10, 2022, under the name QUVIVIQ.[L39660] as the second orexin receptor antagonist approved to treat insomnia following [suvorexant]. … Daridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates