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Displaying results 271 - 280 of 1909 in total
  1. Drug

    C326

    go.drugbank.com/drugs/DB06017
    Experimental

    The drug is composed of an IL-6–binding trimer and a IgG-binding domain. … C326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment

  2. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused ...

    Synonyms: 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid
  3. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)

    Mixtures: AMILORID HCT AL
  4. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes ...

    Mixtures: TANOL 100 ML LOSYON, DEFEKS SURUP, 100 MLProducts: Children Allergy Dye-Free Wal Dryl 20 single doses x 5mL ea, X3 On-the-GO First Aid Topical Analgesic Itch Relief Spray
  5. Drug

    IL-2 pDNA

    go.drugbank.com/drugs/DB05935
    Experimental

    Vical incorporated has initiated a human Phase 1 study of an investigational method of delivering interleukin-2 (IL-2), a potent immune system stimulant, for patients with recurrent metastatic melanoma

    Synonyms: IL-2 pDNA
  6. Drug

    Turpentine

    go.drugbank.com/drugs/DB11120
    Approved

    Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis rea...

  7. Drug

    Befunolol

    go.drugbank.com/drugs/DB09013
    Experimental

    It is currently in experimental status, and is being tested for the management of open angle glaucoma.

  8. Drug

    Adakitug

    go.drugbank.com/drugs/DB05484
    Investigational

    Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. … MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation.

    Synonyms: HuMax IL-8, HuMax-IL-8
  9. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for gl...

    Synonyms: propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoateMixtures: LATANOMED CO50UG/ML+5MG/ML, LATANOMED CO50UG/ML+5MG/ML
  10. Drug

    Anti-inhibitor coagulant complex

    go.drugbank.com/drugs/DB13151
    ApprovedInvestigational

    Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhib...

    Products: /ml Pulver und Lösungsmittel zur Herstellung einer Infusionslösung, /ml Pulver und Lösungsmittel zur Herstellung einer Infusionslösung