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Tobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigationalsuch as β-lactams and cephalosporins. … [L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics
Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/MLCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigationalBimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug
Mixtures: BİMAPRESS DUO 0,3 MG/ML+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, GANFORT® UD SOLUCION OFTALMICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBiperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnA muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: AKINETON 2 MG TABLET, 100 ADET, AKINETON 2 MG TABLET, 50 ADETBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties … aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties.
Mixtures: TANTUM VERDE DUO 22,5 MG+18 MG/15 ML GARGARA, TANTUM VERDE DUO FORTE 45 MG+18 MG/15 ML GARGARAProducts: Nu-benzydamine Oral Rinse, BENZIRIN® ROSA DUCHA LISTA PARA SU USOGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigational[L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP).
Products: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100 MG/MLAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnIt was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. … Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms.
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ALMIZOL 10 MG TABLET, 10 ADET, ULKAMIZOL 10 MG TABLET, 10 ADETSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIn October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease. … It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States.
Mixtures: IFA CERTEZ DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.
Products: QUELICIN 1000 MG/10 ML, ETHICHOLINE INJECTION 100 mg/2 mlEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193698] Ephedrine acts as both a direct and indirect sympathomimetic. … [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.
Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, OPSIS SURUP, 150 MLProducts: RINITALMIT LIQUIDE, 15 ML, Ephedrin Meduna 10 mg/ml InjektionslösungIsopropyl alcohol
go.drugbank.com/drugs/DB02325ApprovedInvestigationalAn isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Mixtures: Sani Wipes, ChloraPrep 20 mg/ml + 0,7 ml/ml Lösung zur Anwendung auf der HautCategories: Compounds used in a research, industrial, or household setting