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Pirlindole
go.drugbank.com/drugs/DB09244ExperimentalThis drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. … Pirlindole is a selective, reversible inhibitor of monoamine oxidase (MAO) subtype A (MAO-A) that is approved in several European and non-European countries for the treatment of major depression.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesGS-100
go.drugbank.com/drugs/DB18337InvestigationalGS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence
Zucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnIt is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions. … Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain.
Leronlimab
go.drugbank.com/drugs/DB05941InvestigationalLeronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn.[L12684] It was first described in the literature in 2001.
Ixekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalAs IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. … In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid Arthritis and plaque psoriasis.
Camostat
go.drugbank.com/drugs/DB13729InvestigationalCamostat mesylate, or FOY-305, is a synthetic serine protease inhibitor. … [A193842,A193848] It was first described in the literature in 1981, as part of research on the inhibition of skin tumors in mice.