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Displaying results 2801 - 2810 of 10000 in total
  1. Drug

    EVT 302

    go.drugbank.com/drugs/DB06057
    Investigational

    It is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.

  2. Drug

    Imipramine

    go.drugbank.com/drugs/DB00458
    ApprovedInvestigational

    They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. … Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines.

    Categories: Antidepressive Agents Indicated for Depression, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: AA PHARMA IMIPRAMINE TABLET 10MG, AA PHARMA IMIPRAMINE TABLET 25MG
  3. Drug

    Ritlecitinib

    go.drugbank.com/drugs/DB14924
    ApprovedInvestigational

    In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further approved by the EMA in September 2023. … [A260122,A260127] Ritlecitinib binds covalently to Cys-909 of JAK3, a site where other JAK isoforms have a serine residue.

  4. Drug

    Vapreotide

    go.drugbank.com/drugs/DB04894
    Investigational

    Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.

  5. Drug

    Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)

    go.drugbank.com/drugs/DB10787
    ApprovedInvestigational

    Mixtures: ADACEL SUSPENSION FOR INJECTION
  6. Drug

    Haemagglutinin-strain A(H3N2)

    go.drugbank.com/drugs/DB15475
    ApprovedInvestigational

    Synonyms: Haemagglutinin-strain A (H3N2), Haemagglutinin-strain A(H3N2)Mixtures: Influvac Suspension for Injection
  7. Drug

    Haemagglutinin-strain A(H1N1)

    go.drugbank.com/drugs/DB15476
    ApprovedInvestigational

    Synonyms: Haemagglutinin-strain A (H1N1), Haemagglutinin-strain A(H1N1)Mixtures: Influvac Suspension for Injection
  8. Drug

    Ethoxzolamide

    go.drugbank.com/drugs/DB00311
    ApprovedWithdrawn

    Its pharmacological activity thus confers the risk for hypokalemia. … Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate.

  9. Drug

    Ligelizumab

    go.drugbank.com/drugs/DB11856
    Investigational

    a greater affinity for free serum IgE and an altered sensitivity to IgE conformation. … Initial trials of ligelizumab suggest a greater efficacy over its predecessor for the treatment of CSU.[A242367]

  10. Drug

    Berdazimer

    go.drugbank.com/drugs/DB18712
    Approved

    [A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and immunocompromised … Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors.