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Bleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalA complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Products: BLEOCIN 15 MG LIYOFILIZE AMPUL, 1 ADET, BLEMISIN 15 MG LIYOFILIZE TOZ ICEREN FLAKON, 1 ADETIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational] was approved in 1996. … [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.
Mixtures: Combivent nebuliser solution in unit dose vial, Duovent Nebuliser solution in Unit Dose Vial 4mlSynonyms: Ipratropium ionRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalRisedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. … It functions by preventing resorption of bone[FDA Label][A959].
Mixtures: RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADET, BONEPLUS D3 75 MG/2800 IU EFERVESAN TABLET, 6 ADETCategories: Heterocyclic Compounds, 1-RingMoroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedVIII, the essential human blood clotting protein that is impaired in Hemophilia A. … Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of
Synonyms: B-domain deleted recombinant factor VIII, Human factor VIII, recombinant B-domain deletedProducts: REFACTO AF 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUC FLAKON, 1 ADET, REFACTO AF 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADETH3B-8800
go.drugbank.com/drugs/DB14017InvestigationalH3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551]. … H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551].
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-PIPERAZINECARBOXYLIC ACID, 4-METHYL-, (2S,3S,4E,6S,7R,10R)-7,10-DIHYDROXY-3,7-DIMETHYL-2-((1E,3E,5R)-1-METHYL-5-(2-PYRIDINYL)-1,3-HEXADIEN-1-YL)-12-OXOOXACYCLODODEC-4-EN-6-YL ESTER, (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl-1-piperazinecarboxylateTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigationalTestosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. … [A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943]
Categories: 3-Oxoandrosten (4) Derivatives, P-glycoprotein inhibitorsSynonyms: 4-androsten-17β-ol-3-one, 17beta-hydroxy-4-androsten-3-oneSimethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigational[A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308] … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.
Mixtures: M A L D I M, E-Z-GAS II GRANULESCategories: Compounds used in a research, industrial, or household settingPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigational[A7624] In the time since its initial approval, pembrolizumab has been granted approval in the treatment of a wide variety of cancers. … Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADET, KEYTRUDA® 100 MGProparacaine
go.drugbank.com/drugs/DB00807ApprovedVet approvedProparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Mixtures: Mydriatic-4Products: PRIMAX EYE DROPS 5 mg/ml, ALCAINE % 0.5 GÖZ DAMLASI, ÇÖZELTİ, 15 MLCoagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalNovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Categories: Increased Coagulation Factor IX Activity, Increased Coagulation Factor X ActivityProducts: NOVOSEVENRT 5 MG, NOVOSEVEN RT 5 MG (250 KIU) ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ