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Emapalumab
go.drugbank.com/drugs/DB14724ApprovedInvestigationalEmapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018. … [A38676, L4840] The approval of emapalumab was followed by the designation of orphan drug, priority review and breakthrough therapy.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDanaparoid
go.drugbank.com/drugs/DB06754ApprovedWithdrawnThe active constituents are heparan, dermatan and [DB09301] [T28], and they are isolated from the porcine intestinal mucosa [FDA Label]. … It is chemically distinct from heparin by containing different protein binding properties, thus has lower cross-reactivity in heparin-intolerant patients.
Categories: Heparin and similars, Blood and Blood Forming OrgansHemoglobin
go.drugbank.com/drugs/DB04945ApprovedInvestigationalWithdrawnIt consists primarily of globin and heme.
Categories: Amino Acids, Peptides, and ProteinsBexagliflozin
go.drugbank.com/drugs/DB12236ApprovedInvestigational[A256408] By inhibiting SGLT2, bexagliflozin reduces renal reabsorption of filtered glucose and increases urinary glucose excretion, which reduces blood glucose levels independently of insulin sensitivity … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.
Categories: Alimentary Tract and MetabolismCefonicid
go.drugbank.com/drugs/DB01328ApprovedIts bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Meningococcal polysaccharide vaccine group A
go.drugbank.com/drugs/DB13889ApprovedInvestigationalMeningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup A. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Mixtures: Menveo Powder and Solution for Solution for Injection, NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONInsulin pork
go.drugbank.com/drugs/DB00071ApprovedInsulin isolated from pig pancreas. Composed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsRilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationaland Muckle-Wells Syndrome (MWS), in adults and children greater than 12 years old. … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome (FCAS)
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsTechnetium Tc-99m nofetumomab merpentan
go.drugbank.com/drugs/DB09336ApprovedWithdrawn[FDA label] Tc-99m nm was developed by Boehringer Ingelheim Pharma KG and FDA approved on September 14, 1992. … It was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as a substance type II (Drug substance) with an active status.[L1650, L1082]
Categories: Amino Acids, Peptides, and ProteinsVelpatasvir
go.drugbank.com/drugs/DB11613ApprovedInvestigationalVelpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … , and reduced all-cause mortality and risk of requiring a liver transplant [A19626].
Mixtures: Sofosbuvir and Velpatasvir, EPCLUSA TABLET 400MG/100MGCategories: sofosbuvir and velpatasvir, sofosbuvir, velpatasvir and voxilaprevir