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LNP-nCoVsaRNA Vaccine
go.drugbank.com/drugs/DB15799ExperimentalThe vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly funded by UK Research and Innovation. … LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells.
Zinc transporter ZIP6
go.drugbank.com/bio_entities/BE0009887TransporterTargetHumansThe SLC39A10-SLC39A6 heterodimer also controls NCAM1 phosphorylation and its integration into focal adhesion complexes during EMT (By similarity). … Zinc-influx transporter which plays a role in zinc homeostasis and in the induction of epithelial-to-mesenchymal transition (EMT) (PubMed:12839489, PubMed:18272141, PubMed:21422171, PubMed:23919497, PubMed
Synonyms: Zrt- and Irt-like protein 6Voxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalBy inhibiting viral protease NS3/4A, voxilaprevir therefore prevents viral replication and function. … Voxilaprevir exerts its antiviral action by reversibly binding and inhibiting the NS3/4A serine protease of Hepatitis C Virus (HCV) [FDA Label].
Mixtures: VOSEVI FILM-COATED TABLETS 400MG/100MG/100MGCategories: Amino Acids, Peptides, and Proteins, sofosbuvir, velpatasvir and voxilaprevirDexbrompheniramine
go.drugbank.com/drugs/DB00405ApprovedDexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Mixtures: Dexbrompherniramine Maleate and Pseudoephedrine Sulfate 6mg/120mg, Coricidin 'd' Nasal and Sinus CongestionSecretin human
go.drugbank.com/drugs/DB09532ApprovedInvestigationalThe hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 [L1875]. … It is indicated for the stimulation of the pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification
Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: Secretin Iberoinvesa Pharma S.L. 100 CU Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungGlycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalGlycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Categories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism ProductsPhenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnIt has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes. … Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor.
Mixtures: Counteract Sinus and Allergy, Contac Cough Cold and Flu CapletsButamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawn[A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. … The FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942]
Denileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigational[A264344] In 2014, it was withdrawn voluntarily from the market due to manufacturing issues; however, the biologics license application (BLA) for denileukin diftitox was resubmitted, and it was approved … approved to treat a human disease in the US.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsThioredoxin reductase
go.drugbank.com/bio_entities/BE0010144TargetMousePromotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components. … Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation.
Synonyms: Thioredoxin and glutathione reductase