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Uridine triacetate
go.drugbank.com/drugs/DB09144ApprovedBy pre-administering with uridine (as the prodrug uridine triacetate), higher doses of 5-FU can be given allowing for improved efficacy and a reduction in toxic side effects [A18578]. … Additionally, orotic acid from the de novo pyrimidine pathway that cannot be converted to UMP is excreted in the urine, accounting for the common name of the disorder, orotic aciduria.
Categories: Alimentary Tract and Metabolism, Nucleic Acids, Nucleotides, and NucleosidesCandoxatril
go.drugbank.com/drugs/DB00616ExperimentalCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
LNP-nCoVsaRNA Vaccine
go.drugbank.com/drugs/DB15799ExperimentalThe vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly funded by UK Research and Innovation. … LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells.
Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approved[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676] … [T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.
Mixtures: Ciprofloxacin and Fluocinolone Acetonide, Ciprofloxacin and Fluocinolone AcetonideCategories: fluocinolone acetonide and antiseptics, fluocinolone acetonide and antibioticsPlasma protein fraction (human)
go.drugbank.com/drugs/DB13968ApprovedInvestigationalThis biologic should come from recovered plasma from whole blood or prepared source plasma. the final product should not include any type of additives. … The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more of 17% should be globulin.
Categories: Amino Acids, Peptides, and ProteinsPeginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalPeginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors. … Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedIt contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis.
Mixtures: Calcium-magnesium With K & Zn and Vitamin D3, Calcium and Mag-potass and Zinc CapCategories: Alimentary Tract and MetabolismMeningococcal polysaccharide vaccine group Y
go.drugbank.com/drugs/DB13888ApprovedInvestigationalMeningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup Y. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.
Mixtures: Menveo Powder and Solution for Solution for Injection, NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONDiatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedAs diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Mixtures: Peritrast 180mg Jod/ml - Lösung zur parenteralen Anwendung, Diatrizoate Meglumine and Diatrizoate SodiumProducts: Gastrografin Röntgenkontrastmittel zur oralen und rektalen AnwendungBone Metastases
go.drugbank.com/conditions/DBCOND0028830Synonyms: Secondary malignant neoplasm of bone and bone marrow