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Dexmethylphenidate
go.drugbank.com/drugs/DB06701ApprovedInvestigationalIt is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181].
Albiglutide
go.drugbank.com/drugs/DB09043ApprovedInvestigationalWithdrawnIt is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline). It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin.
Diacetyl benzoyl lathyrol
go.drugbank.com/drugs/DB11260ApprovedIt is also reported to be a skin conditioning agent.
Diloxanide
go.drugbank.com/drugs/DB08792ExperimentalAlthough it is not currently approved for use in the United States, it was approved by a CDC study in the treatment of 4,371 cases of Entamoeba histolytica from 1977 to 1990.
Guaiacol
go.drugbank.com/drugs/DB11359ApprovedGuaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a pr...
DCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Lobeglitazone
go.drugbank.com/drugs/DB09198InvestigationalUnlike [DB01132], which is a dual PPAR agonist at PPAR-alpha and PPAR-gamma, Lobeglitazone is a pure PPAR-alpha agonist. … It primarily functions as an insulin sensitizer by binding and activating Peroxisome Proliferator-Activated Receptors (PPAR) gamma within fat cells.
Dibromothymoquinone
go.drugbank.com/drugs/DB04646ExperimentalAt higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem] … At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist.
KB001
go.drugbank.com/drugs/DB05222InvestigationalKB001 is a Humaneered™ PEGylated monoclonal antibody fragment for the treatment of life-threatening Pseudomonas aeruginosa infections, a common problem of cystic fibrosis and mechanically ventilated patients.
Glutethimide
go.drugbank.com/drugs/DB01437ApprovedIllicitGlutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.