Guaiacol

DB11359ApprovedSmall moleculeExpectorants

Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.... Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin.

Chemical structure of Guaiacol
Primary indication
It is used medicinally as an expectorant, antiseptic, and local anesthetic.Curator reviewed · 4 structured indications
Formula / weight
C7H8O2 · 124.139 g/mol (avg)
First approval
Canada, 2007
Also known as
2-methoxyphenol · o-guaiacol · o-hydroxyanisole · o-Methoxyphenol · Pyrocatechol monomethyl ether
Code names
Fema no. 2532 · NSC-3815

Resolves to

Compound
UNII6JKA7MAH9CCAS90-05-1ChEMBLCHEMBL13766ChEBI28591PubChem460KEGGD00117
Clinical / RWD
RxNorm5031
Structure
InChIKeyLHGVFZTZFXWLCP-UHFFFAOYSA-NSMILESCOC1=C(O)C=CC=C1
Targets
P02768ALBP00918CA2

What you can answer from here — as of September 13, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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4Structured indicationsCondition, population, route and combination as fields, not prose
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21Marketed productsAcross 3 countries and 14 labellers
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5+ReferencesStructured and connected to the statements they support
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