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Entacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalEntacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols.
Practolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Trefoil Factor 2
go.drugbank.com/drugs/DB15750ExperimentalThey are expressed predominantly in gastric tissues with the source for them being predominantly stromal cells, although expression of TFF2 mRNA transcripts also occurs with tissue macrophages.
Conestat alfa
go.drugbank.com/drugs/DB09228ApprovedDeficiency of C1-inhibitor allows for increased plasma kallikrein activation and subsequent production of bradykinin. … Marketed as the product Ruconest (FDA), this drug is indicated for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.
Cortisone
go.drugbank.com/drugs/DB14681InvestigationalIt has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive.
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainStrontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedStrontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate can...
GC-376 free acid
go.drugbank.com/drugs/DB15796ExperimentalThese results suggest that GC-376, and its metabolites may have therapeutic potential for Covid-19. … The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov infections[A219036,A219056].
Categories: Experimental Unapproved Treatments for COVID-19Ligelizumab
go.drugbank.com/drugs/DB11856InvestigationalInitial trials of ligelizumab suggest a greater efficacy over its predecessor for the treatment of CSU.[A242367] … [A242292] Ligelizumab is currently under investigation for the treatment of chronic spontaneous urticaria (CSU), an autoimmune-driven inflammatory condition.
Perfluorohexyloctane
go.drugbank.com/drugs/DB17823ApprovedInvestigational[A259741] It was approved by the FDA on May 18, 2023 for the treatment of dry eye disease.[L46536]