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Apomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigationalApomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AntagonistsSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolGeraniol
go.drugbank.com/drugs/DB14183ApprovedSensitivity to geraniol may be identified with a clinical patch test. … (FDA) of the United States.
Synonyms: t-geraniol, (E)-NerolPotassium bitartrate
go.drugbank.com/drugs/DB11107ApprovedInvestigationalPotassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. … It is obtained as a byproduct of wine manufacture during the fermentation process.
Perflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalWhen exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. … The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image.
Benralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalBenralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … It is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells, macrophages and neutrophils.
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsMagnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnIt also has antacid properties and is used as a component of some over the counter antacid medications. … Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group [A32782].
Alogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalChemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Acamprosate
go.drugbank.com/drugs/DB00659ApprovedInvestigational[A229073] Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA).
Liraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigational[A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor. … [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34.
Marnetegragene autotemcel
go.drugbank.com/drugs/DB17595ApprovedThese modified cells differentiate to express functional CD18 protein, restoring leukocyte adhesion and extravasation. … Severe leukocyte adhesion deficiency-I (LAD-I) is a genetic disorder leading to frequent life-threatening infections and high fatality risks among affected pediatric patients.
Synonyms: Autologous CD34+ cells transduced ex vivo with a lentiviral vector (Chim-CD18-WPRE) encoding the ITGB2 gene, Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene