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Displaying results 2861 - 2870 of 10000 in total
  1. Drug

    Mevonlerbart

    go.drugbank.com/drugs/DB19416
    Investigational

    Mevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy

    Synonyms: Anti-cat allergen fel d 1 monoclonal anitbody regn-1909, immunoglobulin G4-kappa, anti-[Fel d 1 (Felis silvestris catus (domestic cat) allergen 1)], Homo sapiens monoclonal antibody
  2. Target

    Serine/threonine-protein kinase Nek3

    go.drugbank.com/bio_entities/BE0009497
    TargetHumans

    Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2 … Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons.

    Synonyms: Never in mitosis A-related kinase 3
  3. Indication

    Venous Thrombosis (Disorder)

    go.drugbank.com/conditions/DBCOND0103651
    Drugs: Acenocoumarol · Dextran · Heparin · Picotamide · Protein C · Warfarin
    Synonyms: Acute embolism and thrombosis of unspecified vein, Acute embolism and thrombosis of unspecified deep veins of lower extremity
  4. Drug

    Efgartigimod alfa

    go.drugbank.com/drugs/DB15270
    ApprovedInvestigational

    Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction … and a reduction in electrical nerve impulses.

    Categories: Antineoplastic and Immunomodulating Agents
  5. Drug

    Clesrovimab

    go.drugbank.com/drugs/DB18877
    Approved

    [A273953,A273978] Clesrovimab-cfor was approved by the US FDA in June 2025 for use in infants prior to or during their first RSV season.[L53228,L53233] … to provide passive immunization against RSV infection as an alternative means of protection.

    Categories: Amino Acids, Peptides, and Proteins
  6. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    Segesterone acetate is not an orally active compound, but it is proved to be a potent anti-ovulatory agent when given in implants, vaginal rings or percutaneous gel [A37090]. … It is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component in hormonal contraceptives.

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  7. Indication

    Occlusion, Coronary

    go.drugbank.com/conditions/DBCOND0162588
    Drugs: Acenocoumarol
    Synonyms: Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
  8. Drug

    Simeprevir

    go.drugbank.com/drugs/DB06290
    ApprovedWithdrawn

    Like all NS3/4A inhibitors, simeprevir is a serine protease inhibitor in similarity to [DB08873] and [DB05521] but is classified as a second generation protease inhibitor. … Simeprevir was approved by the FDA in November 2014 and is marketed under the brand name Olysio as oral tablets.

    Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics
  9. Indication

    Internal Haemorrhoids

    go.drugbank.com/conditions/DBCOND0162778
    Drugs: Carvasept · Fluocinolone acetonide · Ichthammol
    Synonyms: Hemorrhoids and perianal venous thrombosis
  10. Indication

    Duchenne Muscular Dystrophy (DMD)

    go.drugbank.com/conditions/DBCOND0040032
    Drugs: Ataluren · Casimersen · Deflazacort · Delandistrogene moxeparvovec · Eteplirsen · Givinostat +3 more
    Synonyms: Duchenne and Becker Muscular Dystrophy, Muscular Dystrophy, Duchenne and Becker Types