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Displaying results 281 - 290 of 10000 in total
  1. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineCategories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor Agonists
  2. Drug

    2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID

    go.drugbank.com/drugs/DB06862
    Experimental

    Synonyms: 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
  3. Drug

    5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID

    go.drugbank.com/drugs/DB07305
    Experimental

    Synonyms: 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
  4. Drug

    5-O-phosphono-alpha-D-ribofuranosyl diphosphate

    go.drugbank.com/drugs/DB01632
    ApprovedWithdrawn

    The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

    Synonyms: 5-O-phosphono-α-D-ribofuranosyl diphosphate, 5-Phospho-alpha-D-ribose 1-diphosphate
  5. Drug

    Dordaviprone

    go.drugbank.com/drugs/DB14844
    ApprovedInvestigational

    [A274391] Dordaviprone has several modes of action, including the activation of mitochondrial caseinolytic protease P (ClpP), antagonism of the dopamine D2 receptor,[L53833] activation of Activating Transcription … Dordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA.

    Categories: MATE 2 Inhibitors, MATE 1 InhibitorsSynonyms: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one, 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-one
  6. Drug

    Fenoterol

    go.drugbank.com/drugs/DB01288
    ApprovedWithdrawn

    Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.

    Synonyms: 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol, 1-(p-hydroxyphenyl)-2-((β-hydroxy-β-(3',5'-dihydroxyphenyl))ethyl)aminopropaneInternational brands: Berotec N
  7. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic nature [A1351].

    Mixtures: T-Chem E2 Rated, D-COL Personal Hygiene Convenience kitCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Zafirlukast

    go.drugbank.com/drugs/DB00549
    Approved

    It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate, 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide
  9. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.

    Mixtures: ROVARTALNF-2, LODITEN 5/5 MG EFERVESAN TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  10. Drug

    Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione

    go.drugbank.com/drugs/DB01496
    ExperimentalIllicit

    Synonyms: Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione