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Displaying results 2891 - 2900 of 8696 in total
  1. Drug

    Acamprosate

    go.drugbank.com/drugs/DB00659
    ApprovedInvestigational

    [A229073] Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. … Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity,

  2. Drug

    Prednisone

    go.drugbank.com/drugs/DB00635
    ApprovedInvestigationalVet approved

    A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.

    Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainProducts: Prednisone D/P, P- Pack Prednisone 20mg, 7- Day Tapering Dose Pack
  3. Drug

    Homatropine

    go.drugbank.com/drugs/DB11181
    Approved

    Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. … It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions.

  4. Drug

    Indium In-111 pentetate

    go.drugbank.com/drugs/DB09425
    ApprovedInvestigational

    Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. … Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography.

  5. Drug

    Tafamidis

    go.drugbank.com/drugs/DB11644
    ApprovedInvestigational

    [A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]

  6. Drug

    Pimethixene

    go.drugbank.com/drugs/DB13292
    Approved

    Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.

    Categories: Antihistamines for Systemic Use
  7. Drug

    Isradipine

    go.drugbank.com/drugs/DB00270
    Approved

    Isradipine may be used to treat mild to moderate essential hypertension.

    Categories: Antihypertensive Agents Indicated for Hypertension, P-glycoprotein inhibitors
  8. Target

    Gamma-aminobutyric acid type B receptor subunit 1

    go.drugbank.com/bio_entities/BE0000217
    TargetHumans

    Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating … Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (PubMed:18165688).

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 1Synonyms: GABA-B receptor 1
  9. Target

    Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

    go.drugbank.com/bio_entities/BE0000628
    TargetHumans

    Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells

    Polypeptides: Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
  10. Target

    Scavenger receptor cysteine-rich type 1 protein M130

    go.drugbank.com/bio_entities/BE0003375
    TargetHumans

    Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. … May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme.

    Polypeptides: Scavenger receptor cysteine-rich type 1 protein M130Synonyms: Hemoglobin scavenger receptor