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Methscopolamine
go.drugbank.com/drugs/DB11315ApprovedMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. … The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Mixtures: Dallergy PE, Allergy DN PESitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256
Mixtures: VELMETIA LP, SITAGLIPTIN E METFORMINA GALENICUMCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesClostridium tetani
go.drugbank.com/drugs/DB09876ApprovedInvestigationalMixtures: Td-pur für Erwachsene und HeranwachsendeLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium _Streptomyces lincolnensis_ in Lincoln, Nebraska. … [A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains
Categories: Heterocyclic Compounds, 1-RingProducts: LINCOCIN 2 ML 600 MG 1 AMPUL, LINKAMIN ENJEKTABL 600 MG/2 ML, 1 ADETDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.
Mixtures: Prezcobix Ped, FURTHAS®R TABLETAS RECUBIERTASCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsDabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022] … [A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: PRADAXA® 150 MG, DABITROM® 150Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
go.drugbank.com/drugs/DB10285ApprovedInvestigationalA and one from subfamily B (A05 and B01, respectively). … It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated factor H binding protein (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily
Synonyms: Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigenMixtures: TRUMENBA SUSPENSION FOR INJECTION IN SINGLE-DOSE PRE-FILLED SYRINGE 0.5MLONT-093
go.drugbank.com/drugs/DB14069ExperimentalIn pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics. … ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp).
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingAtenolol Action Pathway
smpdb.ca/view/SMP0000298Drug actionAtenolol, trade name Tenormin, is a beta blocker prescribed to treat hypertension. Atenolol is a selective beta-1-adrenoceptor antagonist targeting the heart and vascular smooth muscle to inhibit sympathetic activity. Binding of atenolol...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Bisoprolol Action Pathway
smpdb.ca/view/SMP0000300Drug actionBisoprolol (also known as Zebeta) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to reduced heart ...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2