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Displaying results 2911 - 2920 of 10000 in total
  1. Drug

    N-acetyltyrosine

    go.drugbank.com/drugs/DB11102
    ApprovedInvestigational

    N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group. … It is typically administered as a source of nutritional support where oral nutrition is inadequate or cannot be tolerated.

    Mixtures: Aminosyn II 7% With 50% Dextrose, Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)Synonyms: L-N-acetyltyrosine, N-acetyl-L-tyrosine
  2. Drug

    Loncastuximab tesirine

    go.drugbank.com/drugs/DB16222
    ApprovedInvestigational

    Zylonta also received approval in the EU on December 22, 2022. … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success.

    Synonyms: Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine linkerCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    Ocedurenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Ocedurenone has a monoisotopic molecular weight of 503.21 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    GS030-DP

    go.drugbank.com/drugs/DB17847
    Investigational

    It is a component of GS030, an investigational optogenetic treatment, in combination with a medical device GS030-MD.[A259816, L46701] … It targets retinal ganglion cells that encodes a light-sensitive channelrhodopsin, ChrimsonR-tdTomato (ChR-tdT), delivered by an AAV2.7m8 vector.

  5. Drug

    Quinestrol

    go.drugbank.com/drugs/DB04575
    Approved

    The 3-cyclopentyl ether of ethinyl estradiol.

    Synonyms: Estradiol-17-beta 3-cyclopentyl ether, 17-alpha-Ethinylestradiol 3-cyclopentyl ether
  6. Drug

    Moxetumomab pasudotox

    go.drugbank.com/drugs/DB12688
    ApprovedInvestigational

    This antibody was used to generate a recombinant immunotoxin in which a stabilized Fv segment by a disulfide bond is fused to the _Pseudomonas_ exotoxin A (PE38) which does not have the cell-binding portion … CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma.

  7. Target

    Large ribosomal subunit protein uL10

    go.drugbank.com/bio_entities/BE0000743
    TargetShigella flexneri

    Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity).

    Synonyms: 50S ribosomal protein L10
  8. Target

    Large ribosomal subunit protein bL27

    go.drugbank.com/bio_entities/BE0003311
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Found on the solvent side of the large subunit.

    Synonyms: 50S ribosomal protein L27
  9. Target

    Large ribosomal subunit protein uL11

    go.drugbank.com/bio_entities/BE0004326
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

    Synonyms: 50S ribosomal protein L11
  10. Target

    Large ribosomal subunit protein uL22

    go.drugbank.com/bio_entities/BE0009718
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

    Synonyms: 50S ribosomal protein L22