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Norclobazam
go.drugbank.com/drugs/DB17092InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesP-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Linafexor
go.drugbank.com/drugs/DB18031InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGunagratinib
go.drugbank.com/drugs/DB18191ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesElzasonan
go.drugbank.com/drugs/DB18969InvestigationalElzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSevasemten
go.drugbank.com/drugs/DB18983InvestigationalSevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnInterferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leuk...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsInterferon beta-1a
go.drugbank.com/drugs/DB00060ApprovedInvestigationalHuman interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsInterferon beta-1b
go.drugbank.com/drugs/DB00068ApprovedInvestigationalHuman interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors