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P-42 peptide
go.drugbank.com/drugs/DB18610ExperimentalP-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein
Enavogliflozin
go.drugbank.com/drugs/DB18970InvestigationalEnavogliflozin is under investigation in clinical trial NCT06399835 (Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesArketamine
go.drugbank.com/drugs/DB19150InvestigationalArketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSubstance P
go.drugbank.com/drugs/DB19198InvestigationalSubstance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).
Synonyms: Substance P, Neurokinin pCategories: Substance P, antagonists & inhibitorsCamizestrant
go.drugbank.com/drugs/DB19218ApprovedInvestigationalCamizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally … [L64094,L64107] It binds the ligand binding domain of ERα, antagonizing ERα encoded by both wild-type and mutated *ESR1* and inducing proteasome-dependent degradation of the receptor without agonizing
Categories: Estrogen Receptor Antagonists, Selective Estrogen Receptor DegradersNafithromycin
go.drugbank.com/drugs/DB16246InvestigationalNafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsOsalmid
go.drugbank.com/drugs/DB16273InvestigationalOsalmid is under investigation in clinical trial NCT03670173 (Safety and Efficacy Assessments of Osalmid in Multiple Myeloma).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesVitis vinifera seed
go.drugbank.com/drugs/DB16606InvestigationalCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors