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Displaying results 2921 - 2930 of 10000 in total
  1. Drug

    Diethylstilbestrol

    go.drugbank.com/drugs/DB00255
    ApprovedWithdrawn

    A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediol
  2. Drug

    Cefotiam

    go.drugbank.com/drugs/DB00229
    Approved

    One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  3. Drug

    Inobrodib

    go.drugbank.com/drugs/DB17514
    Investigational

    Synonyms: (s)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4s)-4-methoxycyclohexyl)-1h-benzo(d)imidazol-2-yl)piperidin-2-one, 2-piperidinone, 1-(3,4-difluorophenyl)-6-(5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1h-benzimidazol-2-yl)-, (6s)-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Profadol

    go.drugbank.com/drugs/DB17993
    Experimental

    Synonyms: A-2205 free base, M-(1-methyl-3-propyl-3-pyrrolidinyl)phenolCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    2-[4-[(Z)-2-Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]prop-1-enyl]-2-formylphenyl]acetic acid

    go.drugbank.com/drugs/DB03104
    Experimental

  6. Drug

    Fasitibant

    go.drugbank.com/drugs/DB15646
    Investigational

    Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).

    Synonyms: 1-piperazinepentanaminium, .delta.-amino-4-((4-(((2,4-dichloro-3-(((2,4-dimethyl-8-quinolinyl)oxy)methyl)phenyl)sulfonyl)amino)tetrahydro-2h-pyran-4-yl)carbonyl)-n,n,n-trimethyl-.epsilon.
  7. Drug

    TPCA-1

    go.drugbank.com/drugs/DB17058
    Experimental

    TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]

    Synonyms: 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide, 3-thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Captodiame

    go.drugbank.com/drugs/DB09014
    Experimental

    Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. … Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.

    Synonyms: 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamineCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor Antagonists
  9. Drug

    Entinostat

    go.drugbank.com/drugs/DB11841
    Investigational

    Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.

    Synonyms: N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl esterCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Actarit

    go.drugbank.com/drugs/DB20776
    Investigational

    Actarit is a small molecule drug. Actarit has a monoisotopic molecular weight of 193.07 Da.

    Synonyms: 4-acetylaminophenylacetic acid, (p-acetamidophenyl)acetic acid