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Droxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalProvided L-DOPS successfully completes clinical trials, it could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. … Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is
Potassium Iodide
go.drugbank.com/drugs/DB06715ApprovedInvestigationalSaturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radi...
Mixtures: Super Daily No 2, Addamel NTrimethaphan
go.drugbank.com/drugs/DB01116ApprovedInvestigationalA nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.
Mezlocillin
go.drugbank.com/drugs/DB00948ApprovedSemisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Curcuma xanthorrhiza oil
go.drugbank.com/drugs/DB11265ApprovedNutraceuticalCurcumin is a mixture of dicinnamoylmethane derivatives and other phenolic and non-phenolic diarylheptanoids [F114]. … For centuries, _Curcuma xanthorrhiza_ oil has been used as a traditional medicine due to its antibacterial, antispasmodic, antioxidative, antitumor, anti-inflammatory and protective effects [A33160].
Human interferon omega-1
go.drugbank.com/drugs/DB05472InvestigationalIt occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. … The biological activities of IFN-omega 1 and its physiological role are not known to date.
Silver sulfadiazine
go.drugbank.com/drugs/DB05245ApprovedInvestigationalVet approvedSilver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Ivosidenib
go.drugbank.com/drugs/DB14568ApprovedInvestigational[L46287] It was fully approved by the EMA in May 2023.[L46596] … [A248745] Ivosidenib was granted accelerated approval by the FDA in July 2018 for the treatment of relapsed of refractory acute myeloid leukemia in adults.
Methyl nicotinate
go.drugbank.com/drugs/DB13882ApprovedThe action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. … For veterinary purposes, methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and muscle and joint pains [F64].
NNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalIt was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019. … [L11106] It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and Pitt Hopkins Syndromes.