Search

Displaying results 2921 - 2930 of 10000 in total
  1. Target

    Large ribosomal subunit protein uL10

    go.drugbank.com/bio_entities/BE0000743
    TargetShigella flexneri

    Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity).

    Synonyms: 50S ribosomal protein L10
  2. Target

    Large ribosomal subunit protein bL27

    go.drugbank.com/bio_entities/BE0003311
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Found on the solvent side of the large subunit.

    Synonyms: 50S ribosomal protein L27
  3. Target

    Large ribosomal subunit protein uL11

    go.drugbank.com/bio_entities/BE0004326
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

    Synonyms: 50S ribosomal protein L11
  4. Target

    Large ribosomal subunit protein uL22

    go.drugbank.com/bio_entities/BE0009718
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

    Synonyms: 50S ribosomal protein L22
  5. Drug

    TJ003234

    go.drugbank.com/drugs/DB16470
    Investigational

  6. Drug

    GS030-DP

    go.drugbank.com/drugs/DB17847
    Investigational

    It is a component of GS030, an investigational optogenetic treatment, in combination with a medical device GS030-MD.[A259816, L46701] … It targets retinal ganglion cells that encodes a light-sensitive channelrhodopsin, ChrimsonR-tdTomato (ChR-tdT), delivered by an AAV2.7m8 vector.

  7. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    CBDV has also been shown to inhibit the activity of diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2-arachidonoylglycerol (2-AG) [A33296, A33347 … In October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett Syndrome [L2952] and again in February 2018 for treatment of Fragile X Syndrome [L2951].

    Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol, CBD-V
  8. Drug

    Asparagine

    go.drugbank.com/drugs/DB00174
    ApprovedNutraceuticalWithdrawn

    (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) … A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase.

    Mixtures: AMINOPLASMAL-5% E INFUSION, AMINOPLASMAL-10% E INFUSIONSynonyms: (S)-2-amino-3-carbamoylpropanoic acid, L-2-aminosuccinamic acid
  9. Drug

    Unoprostone

    go.drugbank.com/drugs/DB06826
    ApprovedWithdrawn

    Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma. … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid.

    Categories: Prostaglandins FSynonyms: 13,14-dihydro-15-keto-20-ethyl PGF2α
  10. Drug

    Chlorfenson

    go.drugbank.com/drugs/DB05377
    Experimental

    Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.

    Synonyms: 4-Chlorophenyl 4-chlorobenzenesulfonate