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Dimazole
go.drugbank.com/drugs/DB13858ApprovedWithdrawnDimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. … [A176324] Chlorthalidone is considered first-line therapy for management of uncomplicated hypertension as there is strong evidence from meta-analyses that thiazide diuretics such as chlorthalidone reduce
Categories: Antihypertensive Agents Indicated for HypertensionCevimeline
go.drugbank.com/drugs/DB00185ApprovedIt is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Categories: Cholinergic Receptor AgonistAlosetron
go.drugbank.com/drugs/DB00969ApprovedWithdrawnAlosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonin Receptor AntagonistsXanthan gum
go.drugbank.com/drugs/DB11253ApprovedXanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA. It is used as a thickening agent and stabilizer in emulsions.
DPI-221
go.drugbank.com/drugs/DB06121ExperimentalDPI-221 is an investigational drug and a selective agonist for the δ-opioid receptor.
Propiverine
go.drugbank.com/drugs/DB12278ApprovedPropiverine hydrochloride is a bladder detrusor muscle relaxant drug with dual antimuscarinic and calcium-modulating properties for the treatment of OAB [L2317].
Categories: Drugs for Urinary Frequency and Incontinence, Adrenergic alpha-1 Receptor AntagonistsVelmanase alfa
go.drugbank.com/drugs/DB12374ApprovedInvestigationalVelmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. … [A244509] In February 2023, the FDA also approved velmanase alfa for the same indication.[L45295] Velmanase alfa is currently not approved in Canada.
Quinethazone
go.drugbank.com/drugs/DB01325ApprovedQuinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Lenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigational[A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal