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Oxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Categories: Anesthetics for Topical UseProducts: Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-LaryngologieReynoutria multiflora root
go.drugbank.com/drugs/DB14295InvestigationalReynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Fo Ti RootRevakinagene taroretcel
go.drugbank.com/drugs/DB05344ApprovedInvestigational(rhCNTF) (NTC-201-6A cell line) for surgical intravitreal placement. … [L52270] Revakinagene taroretcel delivers CNTF to the retina to lower the extent of neuroregeneration.
Sulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnExcept for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.[L43942] … It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseFutibatinib
go.drugbank.com/drugs/DB15149ApprovedInvestigational[A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September 2022 to treat different types of intrahepatic cholangiocarcinoma. … [L43347] On July 4, 2023, the European Commission granted Conditional Marketing Authorization for futibatinib for the treatment of cholangiocarcinoma.[L47800]
Xenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigational[Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile, but its use in other applications has affected its availability. … [A255183] In December 2022, the FDA approved the use of hyperpolarized Xe-129 for use with MRI for the evaluation of lung ventilation.
Sitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalThe effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]. … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256
Mixtures: CO-SIGLAVITAEVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalSome serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional … Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD).
Categories: Antidepressive Agents Indicated for Depression, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDurlobactam
go.drugbank.com/drugs/DB16704ApprovedInvestigationalIt is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases. … [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of _Acinetobacter baumannii-calcoaceticus_
Bordetella pertussis fimbriae 2/3 antigen
go.drugbank.com/drugs/DB10790ApprovedInvestigationalBordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct
Mixtures: , Suspension for Injection, ADACEL SUSPENSION FOR INJECTION