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Chiglitazar
go.drugbank.com/drugs/DB19023InvestigationalChiglitazar is under investigation in clinical trial NCT06125587 (Chiglitazar/metformin in Non-obese Women With PCOS).
Salts: Chiglitazar sodium, (S)-Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingCortisone
go.drugbank.com/drugs/DB14681InvestigationalA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 4-pregnene-17α,21-diol-3,11,20-trione, pregn-4-en-17α,21-diol-3,11,20-trioneOnternabez
go.drugbank.com/drugs/DB18076ExperimentalSynonyms: [(1S,2S,5S)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanolChrysoeriol
go.drugbank.com/drugs/DB17283ExperimentalSynonyms: 4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, 3'-methoxy-4',5,7-trihydroxyflavoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDazcapistat
go.drugbank.com/drugs/DB18301ExperimentalSynonyms: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide, 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-Cefamandole
go.drugbank.com/drugs/DB01326ApprovedWithdrawnIt is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. It is no longer marketed in the United States.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-D-MANDELAMIDO-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-3-CEPHEM-4-CARBOXYLIC ACID, 5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((HYDROXYPHENYLACETYL)AMINO)-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-8-OXO-, (6R-(6.ALPHA.,7.BETA.(R*)))-1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea
go.drugbank.com/drugs/DB18632ExperimentalSynonyms: 1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea, Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(3-(trifluoromethyl)phenyl)Narsoplimab
go.drugbank.com/drugs/DB16418ApprovedInvestigational[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway. … [A241030] Evidence increasingly points to a role for the complement system in TMA.
Synonyms: IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN, IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN MONOCLONAL OMS721 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL OMS721 .LAMBDA.-CHAIN, DIMERABT-341
go.drugbank.com/drugs/DB08044ExperimentalABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different). [A39406]
Categories: Heterocyclic Compounds, 1-RingSynonyms: (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINEXevinapant
go.drugbank.com/drugs/DB16305InvestigationalSynonyms: (5S,8S, 10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5] diazocine-8-carboxyamide, PYRROLO(1,2-A)(1,5)DIAZOCINE-8-CARBOXAMIDE, N-(DIPHENYLMETHYL)DECAHYDRO-5-(((2S)-2-(METHYLAMINO)-1-OXOPROPYL)AMINO)-3-(3-METHYL-1-OXOBUTYL)-6-OXO-, (5S,8S,10AR)-Categories: Heterocyclic Compounds, 1-Ring