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Estramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Synonyms: Estradiol 3-(N,N-bis(2-chloroethyl)carbamate), 17β-Estradiol 3-(bis(2-chloroethyl)carbamate)Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: Eletop 20 mg-Filmtabletten, Relpax 20 mg - FilmtablettenDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawnIt appears to inhibit formation of a toxic iron-anthracycline complex.
Synonyms: 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione, 2, 6-Piperazinedione, 4,4'-propylenedi-, (P)- (8CI)Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingMethoxy polyethylene glycol-epoetin beta
go.drugbank.com/drugs/DB09107ApprovedInvestigationalMethoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.
Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 50 UG/0.3 ML, MIRCERA® SOLUCION INYECTABLE JERINGA PRELLENADA 50 MCG / 0.3 MLDoxecitine
go.drugbank.com/drugs/DB02594ApprovedInvestigationalThis combination is the first and only approved treatment for Thymidine Kinase 2 deficiency.[L54613, L54618] … It is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair.
Synonyms: MT-1621 COMPONENT 2'-DEOXYCYTIDINE, 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2- yl)pyrimidin-2(1H)-oneCategories: Heterocyclic Compounds, 1-RingBCG vaccine
go.drugbank.com/drugs/DB12768ApprovedInvestigationalWithdrawnBCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
Products: BCG CULTURE SSI 30 MG 4 VIAL, CALGEVAX-BCG 11.25 MG INTRAVEZIKAL ENJEKSIYON IÇIN LIYOFILIZE TOZ IÇEREN AMPUL, 10 ADETAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalFDA approved January 25, 2013. … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesCefalotin
go.drugbank.com/drugs/DB00456ApprovedVet approvedWithdrawnCefalotin is a cephalosporin antibiotic.
Synonyms: CET, 7-(Thiophene-2-acetamido)cephalosporinCategories: Heterocyclic Compounds, 2-RingBacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnBacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. … It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.
Synonyms: 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanateCategories: Penicillin G, Heterocyclic Compounds, 2-RingPovidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnThe clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Synonyms: 1-vinyl-2-pyrrolidinone polymer, 1-ethenyl-2-pyrrolidinone homopolymerMixtures: Leader Artificial Tears 15 mL, Premier Value Eye Drops Mt