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Thalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers. … Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception
Synonyms: N-Phthaloylglutamimide, α-N-phthalylglutaramideInternational brands: K-17Nebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol]. … [A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985]
Categories: Antihypertensive Agents Indicated for HypertensionProducts: CORETEL-NSertaconazole
go.drugbank.com/drugs/DB01153ApprovedSertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseSerdexmethylphenidate
go.drugbank.com/drugs/DB16629Approved[A230698, A230708] Serdexmethylphenidate is a prodrug of the CNS stimulant [dexmethylphenidate], a common first-line treatment for ADHD, that is combined with [dexmethylphenidate] to provide extended plasma … [A230698, A230703] The underlying cause of ADHD is unclear but likely involves dysfunction in dopaminergic and noradrenergic neurotransmission, as evidenced by the clear beneficial effect of CNS stimulants
Categories: Psychostimulants, Agents Used for ADHD and NootropicsBordetella pertussis toxoid antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14388ApprovedInvestigationalBordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, , Suspension for InjectionGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational, cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due to difficulties in extraction … [A182993] The drug was approved by the FDA in 2001 for the treatment of mild to moderate dementia of the Alzheimer's type.
Products: REMINYL 1X TAEGL 8MG, REMINYL 1X TAEGL 16MGOrciprenaline
go.drugbank.com/drugs/DB00816ApprovedA beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway DiseasesTaurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalIt is also being investigated for its role in inflammation and cancer therapy. … Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile.
Categories: Compounds used in a research, industrial, or household settingModafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalThe exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular … Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsGlycol salicylate
go.drugbank.com/drugs/DB11323ApprovedIt is found as an active ingredient and topical analgesic in patches used to provide relief for mild to moderate muscle and joint pain [L2686]. … This drug belongs to the _salicylate_ group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain [L2691].
Categories: Anti-Inflammatory Agents, Non-Steroidal