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Displaying results 2961 - 2970 of 10000 in total
  1. Target

    Potassium channel subfamily K member 10

    go.drugbank.com/bio_entities/BE0013513
    TargetHumans

    K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...

    Polypeptides: Potassium channel subfamily K member 10
  2. Drug

    Rozibafusp Alfa

    go.drugbank.com/drugs/DB19233
    Investigational

    Rozibafusp Alfa is under investigation in clinical trial NCT04058028 (Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)).

  3. Target

    Neuronal acetylcholine receptor subunit alpha-10

    go.drugbank.com/bio_entities/BE0000411
    TargetHumans

    Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits. E...

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-10Synonyms: NACHR alpha-10, Nicotinic acetylcholine receptor subunit alpha-10
  4. Target

    C-X-C motif chemokine 10

    go.drugbank.com/bio_entities/BE0000934
    TargetHumans

    Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:...

    Polypeptides: C-X-C motif chemokine 10Synonyms: IP-10, 10 kDa interferon gamma-induced protein
  5. Target

    Solute carrier family 22 member 10

    go.drugbank.com/bio_entities/BE0003652
    TransporterHumans

    Polypeptides: Solute carrier family 22 member 10
  6. Target

    Cytochrome b-c1 complex subunit 10

    go.drugbank.com/bio_entities/BE0003859
    TargetHumans

    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit...

    Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10
  7. Drug

    Birabresib

    go.drugbank.com/drugs/DB15189
    Investigational

    Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).

  8. Drug

    Polysorbate 20

    go.drugbank.com/drugs/DB11178
    Approved

    Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. … Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications.

    Synonyms: Polysorbate 20
  9. Drug

    Remestemcel-L

    go.drugbank.com/drugs/DB13973
    ApprovedInvestigationalWithdrawn

    Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. … In clinical studies, patients treated with remestemcel-L demonstrated an improvement in their aGvHD and improved survival rates at subsequent days following intravenous infusion [L11022].

    Synonyms: Remestemcel-L
  10. Drug

    Apararenone

    go.drugbank.com/drugs/DB15024
    Investigational

    Apararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).