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Ripasudil
go.drugbank.com/drugs/DB13165InvestigationalRipasudil is a well tolerated medication that is used when other drugs have been proven to be non-effective or cannot be administered. … This medication is available in the form of a 0.4% eye drop solution under the brand name Glanatec.
Categories: Heterocyclic Compounds, 2-RingProducts: GLANATEC OPHTHALMIC SOLUTION 0.4% W/VTubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawnTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. … [A216008] Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a number of plant-derived alkaloids, including [morphine] and [papaverine].
Categories: Heterocyclic Compounds, 2-RingSynonyms: d-tubocurarine, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraraniumGuselkumab
go.drugbank.com/drugs/DB11834ApprovedInvestigationalGuselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. … IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357].
Products: TREMFYA®, TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADETZucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnIt is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions. … Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C19 InhibitorsSynonyms: (Z)-CapsaicinN-methylnicotinamide
go.drugbank.com/drugs/DB08840InvestigationalIt is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine … N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation.
Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 3-(N-Methylcarbamoyl)pyridine, N-Methyl-3-pyridinecarboxamideCefacetrile
go.drugbank.com/drugs/DB01414InvestigationalVet approvedA derivative of 7-aminocephalosporanic acid.
Categories: Heterocyclic Compounds, 2-RingProducts: CELOR ENTRAVENĂ–Z AMPUL 2G, 1 ADET, CELOR ENTRAVENĂ–Z AMPUL 2G, 5 ADETBuclizine
go.drugbank.com/drugs/DB00354ApprovedBuclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging to the _piperazine derivative_ family of drugs.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazineTheobromine
go.drugbank.com/drugs/DB01412InvestigationalTheobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. … It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingPalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalAs of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. … It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnCarbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Carbomer 974 (P), Carbomer homopolymer type B