Cefacetrile is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections. A derivative of 7-aminocephalosporanic acid.
- Mechanism
- Curator reviewed
In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
- Primary indication
- Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.Curator reviewed
- Formula / weight
- C13H13N3O6S · 339.324 g/mol (avg)
- Also known as
- Cephacetrile
Resolves to
RRYMAQUWDLIUPV-BXKDBHETSA-NSMILES[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CC#N)C(O)=OWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Cefacetrile, and which of those have an active Phase 3 trial?
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