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Displaying results 2971 - 2980 of 10000 in total
  1. Drug

    Carbon black

    go.drugbank.com/drugs/DB11980
    Investigational

    [A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416]

    Synonyms: D&C black no. 2, D&C BLACK NO. 2 [II]
  2. Drug

    Potassium nitrate

    go.drugbank.com/drugs/DB11090
    ApprovedInvestigational

    It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. … Potassium nitrate is an inorganic salt with a chemical formula of KNO3.

    Mixtures: Ionite H, Ionite HCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Oxymetholone

    go.drugbank.com/drugs/DB06412
    ApprovedIllicit

    Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes. … The uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events.

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 17β-Hydroxy-2-hydroxymethylidene-17α-methyl-3-androstanone
  4. Drug

    Chloroquine

    go.drugbank.com/drugs/DB00608
    ApprovedInvestigationalVet approved

    [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
  5. Drug

    Tivozanib

    go.drugbank.com/drugs/DB11800
    ApprovedInvestigational

    Marketed by Aveo Oncology, tivozanib is a promising therapy for individuals with RCC who have not been treated successfully with other therapies.[L32524] … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  6. Drug

    Lotilaner

    go.drugbank.com/drugs/DB17992
    ApprovedInvestigationalVet approved

    [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals. … [A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active _in vivo_, while the R-enantiomer is reported to exhibit low biological activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide
  7. Drug

    BMS-690514

    go.drugbank.com/drugs/DB11665
    Investigational

    BMS-690514 has been investigated for the treatment of Breast Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Carnosine

    go.drugbank.com/drugs/DB11695
    Investigational

    Carnosine has been investigated for the treatment of Gulf War Illness.

    Synonyms: L-Carnosine
  9. Drug

    Danusertib

    go.drugbank.com/drugs/DB11778
    Investigational

    Danusertib has been used in trials studying the treatment of Leukemia.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Arhalofenate

    go.drugbank.com/drugs/DB11811
    Investigational

    Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia.