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Displaying results 21 - 30 of 11584 in total
  1. Drug

    Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein

    go.drugbank.com/drugs/DB33819
    Experimental

    Synonyms: Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein
  2. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.
  3. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved by the FDA in November 2023 for use as an enzyme replacement therapy in patients with cTTP. … Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage.

    Categories: Amino Acids, Peptides, and Proteins, Enzymes and CoenzymesSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  4. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  5. Drug

    Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)

    go.drugbank.com/drugs/DB02182
    Experimental

    Synonyms: Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)
  6. Drug

    Gibberella fujikuroi

    go.drugbank.com/drugs/DB15511
    Approved

    Gibberella fujikuroi allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, fusarium moniliforme
  7. Drug

    Benzyl benzoate

    go.drugbank.com/drugs/DB00676
    Approved

    It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. … It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.

    Categories: Scabicides, Insecticides and Repellents, Antiparasitic Products, Insecticides and RepellentsSynonyms: Benzoic acid, benzyl ester, Benzoic acid phenylmethylester
  8. Drug

    Ethylhexylglycerin

    go.drugbank.com/drugs/DB14557
    Investigational

    An emollient solvent with antimicrobial activity.

    Synonyms: Ethylhexylglycerin
  9. Drug

    Human Embryonic Stem Cell-derived M Cell

    go.drugbank.com/drugs/DB15734
    Investigational

    and fibrosis. … However, the difference comes with IMRCs displaying a higher quality of consistency, having stronger immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury

    Synonyms: immunity- and matrix-regulatory cells, Immunity-and-matrix-regulatory cells
  10. Drug

    ALX-009

    go.drugbank.com/drugs/DB17916
    Investigational

    Synonyms: Hypothiocyanite and lactoferrin