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Prothipendyl
go.drugbank.com/drugs/DB12958InvestigationalProthipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: DOMINAL 40MG UTAAnakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalThis drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues.
Synonyms: Interleukin-1 receptor antagonist anakinraCategories: Interleukin-1 Receptor AntagonistSodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalSodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour...
Mixtures: MEHISDIN-P SYRUP, ACD Blood-Pack Units (PL 146 Plastic)Products: Sodium Citrate Blood Pack Units, (PL 146 Plastic), Sodium Citrate Blood-Pack Units, (PL 146 Plastic)Sodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the...
Mixtures: P-Care X, P-Care MProducts: PF %0,9 İZOTONİK SODYUM KLORÜR I.V. İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ, PF %0,9 İZOTONİK SODYUM KLORÜR I.V. İNFÜZYON İÇİN ÇÖZELTİ, 250 ML SETLİAlfuzosin
go.drugbank.com/drugs/DB00346ApprovedBenign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-6...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Teva-alfuzosin Pr, Alfuzosin PH&T 10mg prolonged-release tabletsAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots.
Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PANipocalimab
go.drugbank.com/drugs/DB16257ApprovedInvestigationalNipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases.
Categories: Neonatal Fc Receptor BlockerSynonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonal, Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimerOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigationalOlanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent. Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring. Th...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ZYPREXA 5MG UTA, OLANZAPIN HEUMA 5 MG UTADolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigationalDolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent to...
Mixtures: Triumeq PDCategories: P-glycoprotein substratesSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalsatralizumab formulation developed by Chugai Pharmaceutical and Roche,[L15536] is uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors occurs in a pH-dependent … manner[A218551] - this allows satralizumab to bind an IL-6 receptor until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to act again.
Synonyms: Humanised anti-IL-6 receptor monoclonal antibodyCategories: Interleukin-6 Receptor Antagonist