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Displaying results 21 - 30 of 250 in total
  1. Drug

    Lesinurad

    go.drugbank.com/drugs/DB11560
    ApprovedWithdrawn

    Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptak...

    Products: ZURAMPIC® COMPRIMIDOS RECUBIERTOS CON PELICULA
  2. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Org...

    Products: TINOX® 2.5 MG COMPRIMIDOS, TOBE 2.5 MG COMPRIMIDOS RECUBIERTOS
  3. Drug

    Imipramine

    go.drugbank.com/drugs/DB00458
    ApprovedInvestigational

    Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In...

    Products: IMIPRAMINA 25 MG COMPRIMIDOS, IMIPRAMINA 25 MG COMPRIMIDOS RECUBIERTOS
  4. Drug

    Hydrotalcite

    go.drugbank.com/drugs/DB13322
    ApprovedInvestigationalWithdrawn

    Products: TALCID® COMPRIMIDOS MASTICABLES 500 MG, TALCID COMPRIMIDOS MASTICABLES 500 MG
  5. Drug

    Brivaracetam

    go.drugbank.com/drugs/DB05541
    ApprovedInvestigational

    Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. ...

    Products: BRIVIACT ® 100MG COMPRIMIDOS RECUBIERTOS, BRIVIACT ® 50 MG COMPRIMIDOS RECUBIERTOS.
  6. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole. Benzodiazepine trea...

    Products: ALPRAZOLAM 1 MG COMPRIMIDOS(TRICALMA 1 MG COMPRIMIDOS), BENZOLAM 0.5 MG COMPRIMIDOS
  7. Drug

    Desvenlafaxine

    go.drugbank.com/drugs/DB06700
    ApprovedInvestigational

    Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) c...

    Products: DESVENLAFAXINA50 MG COMPRIMIDOS DE LIBERACIÓN PROLONGADA, VENCONTROL® D COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADA X 50 MG.
  8. Drug

    Zalcitabine

    go.drugbank.com/drugs/DB00943
    ApprovedWithdrawn

    A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA cha...

    Products: COMPRIMIDOS
  9. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepre...

    Mixtures: DORIXINA® RELAX COMPRIMIDOS RECUBIERTOS, DORIXINA® RELAX COMPRIMIDOS RECUBIERTOSProducts: TONALGEN® COMPRIMIDOS 5 MG, TONALGEN® 10 MG COMPRIMIDOS
  10. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thal...

    Products: INMUNOPRIN® 100 MG COMPRIMIDOS RECUBIERTOS