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Displaying results 291 - 300 of 10000 in total
  1. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration. … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.

    Mixtures: Estradiol and Progesterone, Estradiol and Norethindrone AcetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Androgens and Estrogens
  2. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]

    Categories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Non-Selective Monoamine Reuptake InhibitorsSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
  3. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine]. … [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related

    Categories: Alimentary Tract and Metabolism, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Products: Up and Up Acid Reducer Non Prescription Strength, ARNETIN 25MG/ML INJ
  4. Drug

    Erlotinib

    go.drugbank.com/drugs/DB00530
    ApprovedInvestigational

    Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer … This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and other myeloproliferative disorders.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: Erlocip 25mg Film Coated Tablet, Tarceva Film Coated Tablet 25mg
  5. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    [A181397, A181403] Atorvastatin was first synthesized in 1985 by Dr. Bruce Roth and approved by the FDA in 1996. … [T568] It is a pentasubstituted pyrrole [A177415] formed by two contrasting moieties with an achiral heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound.

    Mixtures: ATOZET TABLET 10MG/20MG, CADUET TABLETS 10MG/20MGCategories: atorvastatin and ezetimibe, atorvastatin and amlodipine
  6. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, clomipramine exerts a positive effect on mood. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineCategories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Non-Selective Monoamine Reuptake Inhibitors
  7. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: LOSARPLUS AL 100MG/25MG, LOSARPLUS AL 100MG/25MG
  8. Drug

    Synthetic camphor

    go.drugbank.com/drugs/DB14156
    Approved

    Mixtures: No Touch Chest Rub Rite Aid, Sore No MoreProducts: CBD Clinic - Mild To Moderate Muscle and Joint Pain Relief, Sore No More Warm Therapry Plus CBD 2000mg
  9. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. … [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Seroxat CR Tablet 25mg, Nu-paroxetine
  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Nevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary arterial hypertension but is also additionally notorious for interacting with various anti-anginal … and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614

    Products: VIATHER BY CORNE, VIAGRA 25MG TABLET