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Displaying results 291 - 300 of 10000 in total
  1. Drug

    Clove oil

    go.drugbank.com/drugs/DB11338
    ApprovedNutraceutical

    Clove is native of Indonesia but is now cultured in several parts of the world, including Brazil in the state of _Bahia_. … Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial activity of clove is higher than that of many fruits, vegetables, and other spices [A33133].

    Synonyms: Clove bud oil, Ding xiang bud oil
  2. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. … [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Seroxat CR Tablet 25mg, Nu-paroxetine
  3. Drug

    Coagulation factor VIIa Recombinant Human

    go.drugbank.com/drugs/DB00036
    ApprovedInvestigational

    Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form. … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade.

    Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansProducts: powder and solvent for solution for injection 2mg, powder and solvent for solution for injection 1mg
  4. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration. … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.

    Mixtures: Estradiol and Progesterone, Estradiol and Norethindrone AcetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Androgens and Estrogens
  5. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Nevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary arterial hypertension but is also additionally notorious for interacting with various anti-anginal … and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614

    Products: VIATHER BY CORNE, VIAGRA 25MG TABLET
  6. Drug

    Erlotinib

    go.drugbank.com/drugs/DB00530
    ApprovedInvestigational

    Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer … This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and other myeloproliferative disorders.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: Erlocip 25mg Film Coated Tablet, Tarceva Film Coated Tablet 25mg
  7. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, clomipramine exerts a positive effect on mood. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineCategories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Non-Selective Monoamine Reuptake Inhibitors
  8. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling. … [A175330] It was developed by Daiichi Sankyo Pharmaceuticals and approved in 2002.[A175345, L12882]

    Mixtures: OLMESARTAN CO 1A PH20/25MG, OLMESARTAN CO 1A PH20/25MGCategories: Agents Acting on the Renin-Angiotensin System, olmesartan medoxomil and diuretics
  9. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections. … [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]

    Mixtures: Ciprofloxacin and Dexamethasone, Ciprofloxacin and DexamethasoneCategories: ciprofloxacin and tinidazole, ciprofloxacin and ornidazole
  10. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243] … It binds to mineralocorticoid receptors and functions as aldosterone antagonists.[A178192] It promotes sodium and water excretion and potassium retention.

    Mixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MGCategories: Hormones, Hormone Substitutes, and Hormone Antagonists