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Hydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigationalHydrocodone is a synthetic opioid derivative of codeine.[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations.
Mixtures: Vicodin ES, Vicodin ESProducts: Zohydro ER, Vantrela ERArbutin
go.drugbank.com/drugs/DB11217ApprovedIt has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. … Arbutin was shown to be less cytotoxic to melanocytes in culture compared to [DB09526] [A32942].
Mixtures: Abalone Crystaldouble EX Ampoule, OHUI Sun Science Sun Block EX plus BeigeProducts: IASO White Science EX, Dr Young 2p Brightening UV Sun Block SPF50 PACarbinoxamine
go.drugbank.com/drugs/DB00748ApprovedThis antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. … Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites.
Mixtures: TEMPRA XT NOCHEProducts: Karbinal ERRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous
Products: ROPINIROLO EG, ROPINIROLO EG STADALevosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Categories: Compounds used in a research, industrial, or household settingProducts: LEVOSIMENDAN EG, Levosimendan Carinopharm 12,5 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungPhendimetrazine
go.drugbank.com/drugs/DB01579ApprovedIllicitPhendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Products: Fendique ER, Phendimetrazine Tartrate ERD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approvedL-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants.
Mixtures: DEXTROSA AL 5% EN SODIO CLORURO AL 0.9%, DEXTROSA AL 5% EN SOLUCION SALINACategories: Compounds used in a research, industrial, or household settingGuanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … [L11277] Guanfacine was first described in the literature in 1974.[A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274]
Products: Guanfacine ER, ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 7 TABLETFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Products: STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON, TRANSACT LATPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: PEMETREXED EG, NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE