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Cidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigational[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223] … It suppresses CMV replication through selective inhibition of viral DNA synthesis.
Categories: Heterocyclic Compounds, 1-RingSynonyms: ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid, (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acidEdoxudine
go.drugbank.com/drugs/DB13421ApprovedWithdrawnEdoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. … It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridineTetracosactide
go.drugbank.com/drugs/DB01284ApprovedInvestigationalACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.
Synonyms: ATCH (1-24), corticotropin-(1-24)Products: SYNACTHEN DEPOT 1 MG AMPUL, 1 ADET, Synacthen 0,25 mg/1 ml AmpulleOxacillin
go.drugbank.com/drugs/DB00713ApprovedInvestigationalAn antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5-methyl-3-phenyl-4-isoxazolyl)penicillinRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Mixtures: LIPIVAN E ® 10 MG / 10 MG, ROSUVINA LEGRAND ® E 10/10Categories: Heterocyclic Compounds, 1-Ring, Drugs Used in Diabetes1-(3-METHYLPHENYL)-1H-BENZIMIDAZOL-5-AMINE
go.drugbank.com/drugs/DB07972ExperimentalSynonyms: 1-(3-METHYLPHENYL)-1H-BENZIMIDAZOL-5-AMINE6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
go.drugbank.com/drugs/DB08634ExperimentalSynonyms: 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL5-Hydroxy-N-Propargyl-1(R)-Aminoindan
go.drugbank.com/drugs/DB04307ExperimentalSynonyms: 5-Hydroxy-N-Propargyl-1(R)-AminoindanN-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
go.drugbank.com/drugs/DB04513ExperimentalSynonyms: N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideFlucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin