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Flubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Products: FLUVERNAL TABLETAS DE 500 MG, FLUVERMAL TABLETAS DE 300 MGCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigational[L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.
Mixtures: PAT PO TJIN TJU SAN, ALJIL 150 MG/300 MG/50 MG TABLET, 20 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household settingProducts: Nu-selegiline, SELEGILIN AL 10Esmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule … It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: Brevibloc 100 mg/10 ml - Infusionslösung, Esmolol Amomed 100 mg/10 ml InfusionslösungSulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigational[A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical trials in 1950 but regained interest from the clinical community in the late 1970. … [A255582] Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability.
International brands: Saaz-DSProducts: Sas Tab 500mg, Sas Enema 3gm/100mlColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Rican Premix Powder 1,900 IU/mg, Collis Colistin 1,500,000 IU/g Water Soluble PowderAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigational[A181087, A181406] Some evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within five years) statin use leads to a 20%-22% relative reduction in … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.
Mixtures: TIAZOMET ® A 40/10 TABLETAS, Triveram 20 mg/10 mg/10 mg FilmtablettenCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Ernevod 150 mg Film Kaplı Tablet (12 adet), EVRENZO 150 MG FİLM KAPLI TABLET, 12 ADETBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate.
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalInfection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines.
Products: HEPAGAM B 1560 IU/5 ML IM/IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, HEPATECT CP 500 IU 10 ML FLAKON