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Alfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalA short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analges...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilidePhenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnA drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication)...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersDisulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCinoxacin
go.drugbank.com/drugs/DB00827ApprovedWithdrawnSynthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsFosfomycin
go.drugbank.com/drugs/DB00828ApprovedInvestigationalFosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae. It may also be produced synthetically and is commercially available as the disodium salt for intra...
Synonyms: L-cis-1,2-epoxypropylphosphonic acidProducts: FOMAXIN ® 40MG/ML, Fomicyt 40 mg/ml Pulver zur Herstellung einer InfusionslösungDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedThis current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy [L5200].
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: DIAZEPAM 10 MG/2 ML, Valium Inj Roche 5mg/mlTrifluoperazine
go.drugbank.com/drugs/DB00831ApprovedA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: PMS-trifluoperazine HCl Syr 1.18mg/ml, PMS Trifluoperazine HCl Syrup 11.8mg/mlMifepristone
go.drugbank.com/drugs/DB00834ApprovedInvestigationalMifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye -...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawnLevamisole is an antihelminthic drug that was commonly used for the treatment of parasitic, viral, and bacterial infections. It was manufactured by Janssen and first used in 1969 as an agent to treat worm infestations Levamisole was appr...
Products: PARAKS 40 MG/5 ML ŞURUP, 30 ML, SITRAKS 40 MG/5 ML SURUP, 30 ML