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AZD2315
go.drugbank.com/drugs/DB06540ExperimentalThe drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase
Synonyms: L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, ACETATE (1:2), L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, DIACETATEDapirolizumab pegol
go.drugbank.com/drugs/DB16131InvestigationalDapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus).
Synonyms: Immunoglobulin fab' g1-kappa pegylated, anti-(homo sapiens cd40lg (cd40 ligand, cd40l, tumor necrosis factor ligand superfamily member 5, tnfsf5, tumor necrosis factor related activation protein, trap,Eplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLERENON HEU 50 MG NET, EPLERENON HEU 25 MG NETMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
International brands: Almagel T, Almadrat TMixtures: M A L D I M, ASIPODAN PLUS FORTE ÇIĞNEME TABLETI, 20 ADETAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis … It is used to treat metastatic castration-resistant prostate cancer, hormone-sensitive high-risk metastatic prostate cancer.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol, 17-(3-Pyridyl)androsta-5,16-dien-3beta-olMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approvedMethocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. … [L6295] A combination product with [acetylsalicylic acid] and [codeine] is available in Canada by prescription.[L6295] Methocarbamol was FDA approved on 16 July 1957.[L6265]
Mixtures: MIYOREL 375 MG/300 MG TABLET, 20 ADET, Robaxisal C 1/2Synonyms: (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamateGriseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
International brands: Grison-250, S-FulvinCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 InducersTeicoplanin
go.drugbank.com/drugs/DB06149ApprovedInvestigationalWithdrawnTeicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). … All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety.
Products: TEKOSIT 200 MG IM/IV LIYOFILIZE TOZ ICEREN 1 AMPUL, TARGOCID 200 MG/3 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETMe-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
Synonyms: (2s,3r,4r,5s,6r)-5-(fluoro-18f)-6-(hydroxymethyl)-2-methoxytetrahydro-2h-pyran-3,4-diol, -methyl-4-(F-18)-fluoro-4-deoxy-d-glucopyranosideEtravirine
go.drugbank.com/drugs/DB06414ApprovedInvestigationalOn March 26, 2012, approval was extended for use in treatment-experienced pediatric patients 6 to 18 years of age, weighing at least 16 kg. … Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection.
Categories: Heterocyclic Compounds, 1-Ring, Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase InhibitorProducts: INTELENCE 100 MG TABLET, 120 ADET, INTELENCE TABLET 200 MG