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Displaying results 3011 - 3020 of 10000 in total
  1. Drug

    PW2101

    go.drugbank.com/drugs/DB06483
    Experimental

    The drug was developed by Penwest Pharmaceuticals and in 2005 the FDA issues a Non-Approval letter due to the degree of kinetic variability of PW2101 observed among individuals.

  2. Drug

    Tedizolid

    go.drugbank.com/drugs/DB14569
    ApprovedInvestigational

    [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).

  3. Drug

    Icaridin

    go.drugbank.com/drugs/DB14074
    Investigational

    Icaridin has been commonly used as a topically-applied insect repellent in various countries but was officially licensed for use in the United States in 2001 and Canada in 2012 [L4595]. … Icaridin is reported to be less irritating than [Diethyltoluamide], another common insect repellant, and products containing up to 20% of icaridin are considered safe for long-term use in adults [A39231

    Products: SG Plus Repellent Aroma Mist
  4. Target

    Cytochrome c1, heme protein, mitochondrial

    go.drugbank.com/bio_entities/BE0003854
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c

    Synonyms: Complex III subunit 4, Complex III subunit IV
  5. Target

    Cytochrome b

    go.drugbank.com/bio_entities/BE0000938
    TargetHumans

    Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis

    Synonyms: Complex III subunit 3, Complex III subunit III
  6. Drug

    Bromchlorenone

    go.drugbank.com/drugs/DB20459
    Experimental

    The usage of the INN stem '-renone' in the name indicates that Bromchlorenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  7. Drug

    Elacridar

    go.drugbank.com/drugs/DB04881
    Investigational

    As of August 2007 elacridar was not listed on GSK's product pipeline. Development is assumed to have been discontinued.

  8. Drug

    Sodium chlorite

    go.drugbank.com/drugs/DB13210
    Investigational

    Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].

  9. Drug

    ZYCOV-D

    go.drugbank.com/drugs/DB15892
    Experimental

    As of August, 2020 the candidate is in Phase II clinical trials[A219758]. … Phase I clinical trials of this vaccine candidate were completed in July 2020, with the company reporting successful dosing and tolerance[A219758,L16493].

  10. Drug

    COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection

    go.drugbank.com/drugs/DB16520
    Experimental

    COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen

    Synonyms: COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection, COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's Injection